Peroxisome Proliferator Activated Receptor-δ

Peroxisome Proliferator-Activated Receptor

Peroxisome proliferator - activated receptor

The peroxisome proliferator-activated receptors (PPARs) belong to the nuclear hormone receptor superfamily. All PPARs heterodimerize with the retinoid X receptor (RXR) and bind to specific regions on the DNA of target genes. The discovery of PPARγ as a target of multimodal insulin sensitizers has attracted remarkable scientific interest and had a great impact on the pharmaceutical industry. Thi...

Peroxisome Proliferator-Activated Receptor

Peroxisome Proliferator-Activated Receptor β/δ (PPAR β/δ) as a Potential Therapeutic Target for Dyslipidemia

A natural propenoic acid derivative activates peroxisome proliferator-activated receptor-β/δ (PPARβ/δ)

a Dipartimento di Scienze del Farmaco, Università “G. D'Annunzio”, Chieti-Pescara, Via dei Vestini 31, 66100 Chieti Scalo, Italy b Department of Veterinary and Biomedical Sciences and The Center for Molecular Toxicology and Carcinogenesis, The Pennsylvania State University, University Park, PA 16802, United States c Dipartimento di Chimica e Tecnologia del Farmaco, Sezione di Chimica Organica, ...